Complete the game under the Hard difficulty setting to unlock the Insane difficulty.
New Game +:
Complete very story mission on any difficulty to unlock New Game + mode in the main menu. In NG+ all previously acquired upgrades and evolution levels are kept and available to use on any difficulty.
It's an Epidemic - Complete MEET YOUR MAKER.
I Want Some More - Complete RESURRECTION.
Religious Experience - Meet Father Guerra.
This is a Knife - Acquire a Prototype Power.
Project Closed - Complete a //BLACKNET operation.
Strike, You're Out. - Destroy a Strike Team in 15 seconds or less.
Compulsive Eater - 5 consumes in 10 seconds or less.
Do the Evolution - Acquire 5 Mutations.
Just a Flesh Wound - Dismember a Brawler.
All Together Now - 10 or more kills with a single Black Hole attack.
Back Atcha! - Deflect 5 missiles at enemies using Shield Block.
Two for the Price of One - Simultaneously kill 2 Brawlers using a single Devastator.
Lair to Rest - Destroy a single Lair.
Hijack Be Nimble - Stealth hijack 5 tanks or APCs.
The Floor is Lava - Travel a half mile using only Wall Run, Glide, Jump and Air Dash.
Cannonball! - 20 or more kills with a single Hammerfist dive attack.
You're the Bomb - 10 or more kills using a single Bio-Bomb.
Sic 'em! - Destroy 5 helicopters using Pack Leader.
Over-Equipped - Weaponize 10 vehicles.
The Best Offense - Counter enemy attacks 20 times using Shield.
Arcade Action - Karate kick a helicopter.
I Caught a Big One! - Mount a helicopter using Whipfist.
Vitamin B-rains - Acquire 10 upgrades through Consumes.
Icarus - Reach the highest point in the world.
One by One - Stealth Consume 50 Blackwatch troopers.
Wanted Man - Trigger 50 alerts.
The Mad Scientist - Complete NATURAL SELECTION.
Something to Live For - Complete FALL FROM GRACE.
What a Bitch - Complete LABOR OF LOVE.
Follow Your Nose - Find all BlackBoxes.
Up to No Good - Defeat all Field Ops teams.
Road Rage - Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
Who Watches the Watchers? - Consume 10 //BLACKNET targets.
Hard to Please - Acquire a Mutation in each of the 5 categories.
Anger Management - Destroy 5 vehicles using a Finisher.
So Above It All - Spend at least 25 consecutive seconds in the air (helicopters don't count).
Eating Your Way to the Top - Acquire 30 upgrades through Consumes.
Spindler's Search - Destroy all Lairs.
//BLACKNET Hacker - Complete all //BLACKNET dossiers.
All Growed Up - Fully upgrade Heller.
Master Prototype - Complete the game on HARD difficulty.
Murder your Maker? - Complete the game.
Finally Full - Acquire all 46 upgrades through Consumes.
Platinum Trophy - Earn all Bronze, Silver, and Gold trophies.