View the following alternate endings by completing the game with the corresponding amounts of little sisters harvested:
ENDING - HOW TO UNLOCK
Ending A - Save all the Little Sisters you encounter in the game.
Ending B - Harvest all the Little Sisters you encounter in the game.
C - Harvest some of the Little Sisters in the game, and save the rest.
((very similar to Ending B but with a different tone)
Power to the People Station locations:
Find the following Power to the People stations in the corresponding locations:
POWER TO THE PEOPLE STATION - LOCATION
Apollo Square - Hestia on 4th floor
Arcadia - Tree farm
Farmer's Market - Winery cellar on bottom floor
Fort Frolic - Sinclair's spirits in basement
Fort Frolic - Le marquis d'epoque
Hephaestus - Across from gatherer's garden
Hephaestus - Kyburz's office
Neptune's Bounty - Freezer on bottom floor
Olympus Heights - Fontaine's apartment on opposite side
Olympus Heights - Sander cohen's private chambers
Pt. Prometheus - Atrium
Pt. Prometheus - Optimized eugenics
BioShock 2: Sea of Dreams trailer:
To unlock the Bioshock 2: Sea of Dreams trailer, complete the game and go to the "Extras" menu to view it.
An easy way to get money is to corrupt a slot machine by using the Incinerate Plasmid on it. You will win every time you play it.
Alcoholic beverages can be turned into Molotov cocktails by igniting them with a source of flame such as the Incinerate Plasmid or Chemical Thrower. Pick up the alcohol bottle with the Telekinesis Plasmid and throw it at a target.
1. Security Expert - In twilight fields mortuary on a shelf.
2. Speedy Hacker - In painless dental in the corner.
3. Wrench Jockey: In kure all, through crawl shaft on the floor.
4. Hacker's Delight - In the eternal flame crematory, activate the furnace.
5. Static Discharge - In the surgery foyer next to steinman's lab.
6. Eve Link - Purchase at gatherer's garden.
7. Armored Shell - Purchase at gatherer's garden.
8. Wrench Lurker - Lower wharf, near the edge of the walkway.
9. Focused Hacker - Inside fontaine fisheries next to first pneumo tube.
10. Medical Expert - On the lower wharf where you enter the level.
11. Extra Nutrition - Purchase at gatherer's garden
12. Security Evasion - On the lower left area of arcadia. It will be next to a dead houdini splicer surrounded by four thuggish splicers.
13. Hacking Expert - In the research laboratories on the desk.
14. Shorten Alarms - Purchase at gatherer's garden
15. Human Inferno - Purchase at gatherer's garden
16. Eve Link 2 - To the left of the entrance, near the circus of value and u-invent machine
17. Photographers Eye - Bottom floor of the winery in the bunk.
18. Alarm Expert - On the balcony of the fleet hall.
19. Frozen Field - Search matin finnegan's corpse.
20. Extra Nutrition 2 - Downstairs behind the main stairway of the main atrium near eve's garden.
21. Electric Flesh - In Cohen's dressing room. Complete his masterpiece, then go to the room beside the upstairs projection booth.
22. Medical Expert 2 - Complete sander's masterpiece.
23. Hacking Expert 2 - Purchase at gatherer's garden.
24. Bloodlust - Must be invented in the u-invent machine.
25. Booze Hound - Must be invented in the u-invent machine
26. Hacker's Delight 2 - Must be invented in the u-invent machine.
27. Frozen Field 2 - In bottom corner of the central core on a desk.
28. Security Evasion 2 - In Lower Heat Loss Monitoring on a desk.
29. Damage Research - In secret crawlspace in the back of the lower workshops.
30. Shorten Alarms 2 - In geothermal core.
31. Clever Inventor - In suchong's apartment on a desk.
32. Electric Flesh 2 - In fontaine's apartment on a desk.
33. Speedy Hacker 2 - Purchase at gatherer's garden.
34. Wrench Lurker 2 - Purchase at gatherer's garden.
35. Medical Expert 3 - Suchong's clinic on 2nd floor.
36. Focused Hacker 2 - Hestia building on 4th floor.
37. Safe Cracker 2 - Autopsy room of the 1st floor of little wonders.
38. Alarm Expert 2 - In point prometheus in filing cabinet.
39. Damage Research 2 - In library 2nd floor on a desk.
40. Hacker's Delight 3 - In failsafe armory next to rosie helmets.
41. Human Inferno 2 - Purchase at gatherer's garden.
42. Safecracker - Rescue 6 little sisters.
43. Armored Shell 2 - Rescue 15 little sisters.
44. Prolific Inventor - Rescue 18 little sisters.
45. Natural Camoflage - Research level 2 houdini splicers.
46. Scrounger - Research level 2 leadhead splicers.
47. Sportboost - Research level 2 thuggish splicer.
48. Photographer's Eye 2 - Research level 2 rosie.
49. Wrench Jockey 2 - Research level 2 bouncer.
50. Extra Nutrition 3 - Research level 4 spider splicer.
51. Sportboost 2 - Research level 4 thuggish splicer.
52. Static Discharge 2 - Research level 4 leadhead splicer.
53. Security Expert 2 - Research level 2 security bot.
To earn a secret trophy, take a picture of Sander Cohen's dead body.
Big Daddy hint:
The Hypnotize Big Daddy Plasmid and the Natural Camouflage Tonic are required for this trick. Simply use the Hypnotize Big Daddy Plasmid on a Big Daddy so that he thinks you're a Little Sister and protects you. Now here's the fun part; just find and attack another Big Daddy and your Big Daddy will attack it to protect you.
Free Health Packs hint:
Instead of buying health packs at health stations for $10, get them for free by smashing the machines with your wrench. After a couple hits, between 1-3 health packs should lie on the floor for you to grab, for free.
While shooting either the Crossbow or the Grenade Launcher, rapidly reload by pressing the left trigger, then quickly after pressing the right trigger. This allows you to start shooting without having to wait longer (several seconds) for your weapon to reload. This is especially useful against powerful enemies like Big Daddies.
Sander Cohen hint:
You will meet Sander Cohen about halfway through the game, a crazy artist dude. When you complete the level, you can just leave him or kill him. If you kill him at that point, you can't get one of the trophies; "Find Cohen's Room." A while later you will stumble onto Cohen's apartment. If he's alive, two Splicers will be dancing in the main room, with Cohen watching from his locked private room. Kill the Splicers and then Cohen comes out to fight you, thus unlocking the door and allowing you to earn the trophy.
Security Drone Manipulation:
Temporarily disable security drones by using a blast of the Electric Shock Plasmid before you do anything else in a room. Then, run up to them within five seconds and hack them. You can hack while the game is on virtual "pause." You'll have security drones on your side for the rest of the time you are in a fight afterward.
Telekinesis Drop hints:
-While using the Telekinesis Plasmid, it is possible to drop the item you are holding instead of throwing it across the room. To do this you must have an item currently being held. Pick up any item with the Telekinesis Plasmid selected. Using the LT button, keep holding the item, and donít let go of the LT button. When youíre ready to drop the item, press the RB button to open your weapons menu and, in the transition of the weapons menu opening, let go of the LT button. Select your weapon and the item will drop safely to your feet. If done correctly, the item falls at your feet, instead of being thrown, which makes the item easier to find when you need it. A simpler way to drop the item you're holding is to just hit 'X'. So, with the Telekinesis Plasmid armed, hold LT to TK something to you. While it is 'in your face', press X to drop it on the ground--with no need to switch to weapons.
Restoring hacked robot's health:
After hacking a robot it will start firing at your enemies. If the robot gets hit it will begin to lose health, catch on fire, and eventually blow up. To stop this from happening, deactivate the robot (press A while pointing at the robot), then reactivate it a few seconds later. This will make the robot have full health again.
Avoid Splicers, Bots, Big Daddies and turrets:
Research the Houdini Splicers until you get the Natural Camouflage Tonic. If you have this equipped, you will become invisible if you remain still. This will protect you from Splicers, Big Daddies, and Bots if you set off an alarm. If you move again you will become visible. You cannot become invisible if an enemy sees you. If you are invisible and an enemy besides a Bot touches you, they will see you. The cameras and turrets also cannot see you if you are invisible.
Getting the Little Sister behind the gate in Fontaine Fisheries:
In Fontaine Fisheries, a Big Daddy and a Little Sister are behind a gate. You can either kill the Big Daddy later and come back for the Little Sister or you can kill the Big Daddy then use Telekinesis to drag his corpse over to the gate. When the Little Sister gets close enough (because they always stay near the corpse of a Big Daddy),† you can rescue or harvest her through the gate.
Reaching Fontaine's penthouse hint:
The code to get to Fontaine's penthouse is from the diary, and as follows: "5744".
Save game hint:
After you become a Big Daddy, make a new saved game. You are near the end of the game. If you missed something you can go to the bathysphere and explore Rapture again. Also, you are a Big Daddy now so the splicers will not harm you, security cameras will not set off alarms, etc.
Easy kills hint:
From the start you will have a wrench and the Electric Bolt Plasmid in your inventory. Using these in rapid succession against most Splicers can often result in an fast kill. First, shock the Splicer. Before the convulsion ends, switch out the wrench, aim high, and hit the Splicer over the head. However, best way to eliminate the agile Spider Splicers is to unleash a few clips of anti-personnel ammo, preferably from the machine gun.
Atlas Fontaine strategy:
Atlas Fontaine, the final Boss, has three different styles of attacks: Flame Plasmid Form, Ice Plasmid Form, and Electric Plasmid Form. The easiest way to defeat him during the first part is to use your Ice Plasmid and freeze him, then switch to your Telekinesis Plasmid. Grab an explosive tank and throw it at him. Also, if desired, just use your telekinesis. He is predictable if you are far away from him. Wait for him to throw a fire ball at you, then move out of the way. He will keep running past you; use this chance to fire the machine gun, which does the most damage to him. Once he goes back to his chamber to gain his life back, change to the Flame Plasmid and get ready for some bots. Once he starts his routine of fire and run, blast again him with the Flame Plasmid . The more you blast him, the faster he loses life. Continue to use the machine gun while he is aflame. He will now go back to his chamber one last time and then have electrical powers. Keep your Flame Plasmid ready. This time, shoot him with the Flame Plasmid and he will run for the water. Once he jumps in the water and comes back out, hit him with it again. Be aware that there are splicers around. Also set them ablaze to get some extra life. There are many different ways to defeat him but this seemed to be the easiest.
-The easiest way to defeat Atlas is to have the fully upgraded shotgun and the Decoy ability. After you drain his Adam, drop a decoy and, while Atlas is attacking it, use the shot gun. After you have used all four rounds, quickly cast Decoy again, reload your shotgun, then begin shooting him again. Repeat this until you have to drain his Adam. Once again, reload your shotgun and Plasmids before you drain his Adam, then start over using Decoy and the shotgun. Use Health Packs as needed and ignore any Splicers in the area as they will be paying attention to your Decoy just like Atlas.
Big Daddies strategy:
After obtaining the crossbow and at least five Trap Bolts, it is easy to take down a Big Daddy. Face a wall and stand about three feet away. Make sure it is not something that the bolts can bounce off of, and also make sure you have a good ten foot long straight wall. Once you are better skilled at this technique you can try for shorter lengths if desired. Point straight ahead and fire out a bolt before taking about two steps to the left or right, depending on which way the Bid Daddy is and your location, and fire another. Fire all five bolts out, then shoot the Big Daddy once with anything. If done correctly, it will run through the line of traps, taking enough health down so he can be killed with a few shots of any other weapon. Note: This may not work in an open area because Big Daddies strafe often. If you have the damage increase for the crossbow, it will only take three or four bolts to kill him. Do not crouch while setting up the traps. If the Big Daddy walks another way and gets out of sight, you might need to go back to get him. If you do get him, you can crouch under the set traps. An easy way to trigger bolt traps is to pick up something with Telekinesis and drag the object through it.
-Get your shotgun fully upgraded (power to the people stations, rate of fire, and damage upgrades) and simply use your old 00 buck. After killing them, get the Little Sister and all the money they had on them. This can result to very little damage from Big Daddies. Aim for the head to cause more damage. Note: This was done under the Easy difficulty setting.
-After acquiring the Security Bullseye Plasmid, set off an alarm either by hacking or being spotted by a security camera, then throw the Security Bullseye at the Big Daddy. You may have to do this twice depending on how much health the Big Daddy has when starting out. Try to avoid the battle because the crossfire and exploding bots will damage you. The only problem with this technique is that once the Big Daddy is taken down, the bots will come after you. Be prepared to either run and hide, or fight them off.
-Usually, Little Sisters will return to the same corpses several times. You can use this to your advantage by placing the corpse near a security camera with the Telekinisis plasmid, then wait for her to show up and tag her Big Daddy with the Security plasmid. He will keep returning if he survives. You can stay in the same safe location and wait for the bots to finish off the Big Daddy.
-Just use two Trap Bolts in Poseidon. If you get the damage increase for the crossbow, aim for the face.
Frank Fontaine strategy:
When you first enter the room, hit him with the tool the Little Sisters gave you and fight him when he throws you off. Once he is back on the bed, run up and hit him again with the tool to drain his Adam. This works much faster due to him only have four or five jars of Adam to drain, and the fights are not very long afterwards.
Peach Wilkins strategy:
When the dark cloud envelopes the icy battlefield where you face Peach Wilkins, save the game and locate the hostile turret at the end of the room when the cloud clears. Load the game and run to it before the cloud clears so you can quickly freeze or shock it, then hack it so it shoots your enemies. Crouch down by the area to your right when facing the turret. There are some barriers here to protect you from enemy fire. However, to avoid damage by Wilkins' grenades, keep Telekinesis as your active Plasmid. He will avoid the turret's fire, but as long as you stay behind the barriers by the turret, he will stay at a safe distance. This gives you time to calmly return his grenades using Telekinesis until he is dead. The turret will take out most of the Splicers. This method makes things much easier because it eliminates the hectic "run around and whack people with the wrench" strategy that is your only other option. That turret, if not used as an ally, would probably be the main cause of your death, along with the bots triggered by the security camera. However, by hiding near the allied turret, you also hide from the camera's view.
-When fighting a Rosie, use armor piercing rounds with the machine gun or pistol. Another effective way of killing them is by launching frag grenades and running out a door. The Rosie will follow you, fire proximity mines at the door, and be damaged or destroyed when it walks through it will.
-While in levels that have more than one Little Sister in them, there are sometimes Rosies roaming the level alone. The following only happens if you have already harvested or saved at least one but not all the Little Sisters in that level. The lone Rosie will walk up to one of the many holes in the walls through which the girls crawl through and bang on the metal before waiting. Then, it will help a Little Sister jump down from the opening. The girl will then lead the Rosie throughout the level. Therefore, when hunting these formidable enemies, do not attack or ignore a Rosie if it walks alone (as long as in the pause screen it says that there is still at least one Little Sister remaining). Rather, follow it and wait for it to summon a Little Sister out of the wall, then attack it using whatever strategy suits you. If you attack it when it's alone you will not get to harvest or save any Little Sister as a reward for killing it.
Security robots strategy:
If you must fight a stationary security robot (RPG, etc.), use Telekenesis to grab a crate or pallet and hold it in front of you until you can find a place to hide and plan what to do next. The item you hold up will block some attacks.
Chompers Dental key hint:
The Chompers Dental key in the Medical Pavilion is acquired by using Telekinesis through the broken window to the left of the door. There is a corpse hanging over the broken window. The key must be grabbed with Telekinesis because it is hanging on a wall on the other side of the window. You can get Telekinesis in an area near here. You will need to get that first, but do not follow the arrow back to the rubble that you need to get rid of until exploring Chompers Dental. There is a safe and other good items to be found inside. Note that both Telekinesis and Chompers Dental are near where you find the shotgun.
Weapon Upgrade Station locations:
-1. In Peach Wilkins' hideout (Neptune's Bounty), bottom floor. As soon as you come downstairs it is directly in front of you.
-2. On the way to Farmer's Market in Arcadia, the station is located to the left after you go up the first stairs coming from Tree Farm.
-3. The Winery's basement in Farmer's Market. There is a flooded area with one of them attached to the wall. It is in front of you when you come down the stairs; just keep going forward.
-4. In Fort Frolic, from the Atrium bottom floor, go towards the bathrooms. Then, move right and follow the path until you see some small stairs to your right leading up to a door. Go inside then go down into the basement. The basement is filled with cigars and the like. The upgrade station is on the wall.
-5. Go to Poseidon Plaza in Fort Frolic. Go to the other end of the bottom floor (the opposite end of where you enter). Go into Sinclair Spirits (the room that has a corpse on a sort of "altar"). In the basement of this store is the station.
-6. In Hephaestus Core Room, go down to the bottom floor and run around (literary). Eventually you will see it attached to the wall.
-7. In Hephaestus, Kyburz's office. It is attached to the left wall (back turned to the entrance) in the rear of the room.
-8. At the bottom floor of the Mercury Suites area, on the back of the center pillar.
-9. In Sander Cohen's secret room, in the Olympus Heights' Mercury Suites area.
-10. Go to Atlas' Headquarters in Apollo Square (Fontaine's Home For The Poor area). It is located on the fourth floor. Go down the stairs in the room and look to the right to find the station in front of you.
-11. When you enter Point Prometheus and chase Fontaine, you will eventually end up in a little square and Fontaine will go behind a locked Museum door. At the opposite end of this square (from where you came) is a dead Big Daddy. Next to it is the upgrade.
-12. In the Voice changing labs in Point Prometheus; one of the labs has it.
Audio Dairy locations:
Find the following Audio Diaries by searching the corresponding locations. Note: there are122 audio diaries. They are required for the "Historian" trophy.
AUDIO DIARY - SPEAKER - LOCATION
New Year's Eve Alone - Diane McClintock - Kashmir Bottom Floor on top of table
Hole in the Bathroom Wall - Steve Barker - Kashmir Restaurant in the "Dames" bathroom
Released Today - Diane McClintock - Medical Pavilion Foyer on the reception desk
Adam's Changes - Steinman - Emergency Access on the desk
Higher Standards - Steinman - Medical Pavilion Foyer near entrance on wall
Parasite Expectations - Andrew Ryan - Medical Pavilion Foyer near surgery on desk
Limits of Imagination - Steinman - Medical Pavilion Foyer by Eternal Flame's wall
Love for Science - Tenenbaum - Medical Pavilion Foyer near health station
Vandalism - Andrew Ryan - Medical Pavilion Foyer near vending machines
Freezing Pipes - McDonagh - Medical Pavilion Foyer near bottom of stairs
Surgery's Picasso - Steinman - Eternal Flame entrance near memorial
Enrage Trial - Suchong - Kure All corner of main room
Plasmids are the Paint - Suchong - Painless Dental desk in the corner
Useless Experiments - Tenenbaum - Dandy Dental floor near entrance
Testing Telekinesis - Suchong - Dandy Dental on the floor by Gatherer's Garden
Symmetry - Steinman - Surgery Foyer wall by debris pile
Aphrodite Waking - Steinman - Surgery desk in northern OR
Not What She Wanted - Steinman - Surgery in the corpse on table the doctor worked on
Gatherer's Vulnerability - Steinman - Lounge on the floor by Gatherer's Garden
Bathysphere Keys - Sullivan - Lower Wharf under south end of the boardwalk
Timmy H. Interrogation - Sullivan - Lower Wharf in the water of the interrogation room
Fontaine Must Go - Andrew Ryan - Lower Wharf crawl under the metal grating by the pipes
Finding the Sea Slug - Tenenbaum - Upper Wharf table by the stairwell entrance
Masha Come Home - Marista Lutz - Upper Wharf floor by Little Sister
Picked Up Timmy H - Sullivan - Upper Wharf near Little Sister in the corpse
Watch Fontaine - Andrew Ryan - Upper Wharf next to the Circus of values machine
Have My Badge - Sullivan - Wharfmaster's Office on desk
Adam Discovery - Tenenbaum - Upper Wharf in crate below the wharfmaster's office
Eden Leaking - McDonagh - Upper Wharf hallway going towards Jet Postal
Fontaine's Smugglers - Tenenbaum - Jet Postal bench in glass tube
Death Penalty in Rapture - Andrew Ryan - Jet Postal desk by vending machine
Smuggling Ring - Sullivan - Fighting McDonagh center bar table
Working Late Again - Andrew Ryan - Fighting McDonagh window bar table
Rapture Changing - McDonagh - Fighting McDonagh desk in basement office
Meeting Ryan - McDonagh - Fighting McDonagh crawl through the water-filled ventilation shaft towards the Gene Bank
Arresting Fontaine - McDonagh - Fighting McDonagh room #6 upstairs
Saw Masha Today - Marista Lutz - Fighting McDonagh room #7 upstairs
Putting the Screws On - Peach Wilkins - Freezer Bottom Floor next to safe
Meeting With Fontaine - Peach Wilkins - Storage Cave ground by crates
Kraut Scientist - Frank Fontaine - Control Room Lower Floor in locked storage cave
Offered a Deal - Peach Wilkins - Submarine Bay on dock towards Arcadia
Seeing Ghosts - McDonagh - Tea Garden floor left of entrance
Mass Producting Adam - Tenenbaum - Tea Garden floor near chairs
Big Night Out - Dieter Sonnekalb - Tea Garden floor near ghost bench
Arcadia Closed - Langford - Tea Garden desk near Gene Bank
The Market is Patient - Andrew Ryan - Waterfall Grottos bench near U-Invent
Early Tests Promising - Langford - Waterfall Grottos near water wheel
Offering a Better Product - Andrew Ryan - Waterfall Grottos near water wheel
Heroes and Criminals - Diane McClintock - Waterfall Grottos in locked machinery room
Shouldn't Have Come - Mariska Lutz - Lower Rolling Hills bench near stairs
The Saturnine - Langford - Lower Rolling Hills cave behind waterfall
Arcadia and Oxygen - Langford - Tree Farm near crate at entrance
What Won't They Steal - Langford - Research Laboratories near entrance
Teaching an Old Hound - Langford - Research Laboratories table in second room
Lazarus Vector - Langford - Langford's Office in Julie Langford's body
Lazarus Vector Formula - Langford - Langford's Office in Julie's wall safe
Maternal Instinct - Tenenbaum - Tree Farm on the steps towards Farmer's Market
Bee Enzyme - Tasha Denu - Farmers Market ground near pneumo tube
First Encounter - Andrew Ryan - Farmers Market near Bouncer corpse
Hatred - Tenenbaum - Farmers Market lower storage room desk
Desperate Times - Andrew Ryan - Farmers Market near freezer crawlspace
Pulling Together - Andrew Ryan - Farmers Market on meat market counter
Water in Wine - Pierre Gobbi - Farmers Market near winery sign
Adam Explained - Tenenbaum - Silverwing Apiary near entrance counter
Functional Children - Tenenbaum - Winery on the back table
The Great Chain - Andrew Ryan - Arcadia Metro Station bench right of entrance
Musical Insult - Sander Cohen - Fleet Hall Theatre storage room near guitar
The Doubters - Sander Cohen - Cohen's Collection downstairs table
Come to the Record Store - Cobb - Southern Mall on table outside of the restroom
The Wild Bunny - Sander Cohen - Sophia Salon in closet behind counter
Artist's Feud - Sullivan - Cocktail Lounge above the bar safe
Fancy Cigarettes - Albert Milonakis - Le Marquis D'Epogue downstairs near corpse
The Iceman Cometh - Martin Finnegan - Frozen Tunnel left of entrance hall
Stood Up Again - Diane McClintock - Upper Atrium top of stairs near Fleet Hall's entrance
Guns Blazing - McDonagh - Robertson's Tobaccoria table near entrance
Pregnancy - Jasmine Jolene - Eve's Garden under bed behind stage
It's All Grift - Hector Rodriguez - Eve's Garden on the bar
Fontaine's Army - McDonagh - Sir-Prize left of stairs in crate
Bumb Culpepper? - Sullivan - Pharoah's Fortune on pool table upstairs
Ryan's Stableboy - Anna Culpepper - Rapture Records behind entrance counter
Requiem for Andrew Ryan - Sander Cohen - Projection Booth on office table
Ryan Takes F Futuristics - McDonagh - Hephaestus Bathysphere St. crate near the Circus of Values machine
Scooping the Gate - Kyburz - Outside Ryan's Office near the Circus of Values machine
Stopping Ryan - McDonagh - Ryan's Office first corpse on right
Going to Heat Loss - Anya Andersdotter - Outside Ryan's Office forth corpse on right
A Man or a Parasite - Andrew Ryan - Hephaestus Core desk outside of bunks
Fontaine's Legacy - McDonagh - Hephaestus Core near Vita-Chamber on the walkway
Assassin - Anya Andersdotter - Hephaestus Core near Gatherer's Garden
Kyburz Door Code - Pablo Navarro - Heat Loss Monitoring floor in the corner
Genetic Arms Race - McDonagh - Lower Heat Loss Monitoring on desk in flooded area
Getting a Break - Pablo Navarro - Lower Heat Loss Monitoring on desk near tonic
Impossible Anywhere Else - Andrew Ryan - Hephaestus Core desk at bottom walkway
Running Short on R-34s - Pablo Navarro - Hephaestus Core desk outside the Workshops entrance
Device Almost Finished - Kyburz - Lower Workshops office desk at bottom of the stairs
Great Chain Moves Slowly - Andrew Ryan - Kyburz's Office desk in back of room
The Dream - Kyburz - Lower Workshops corpse in middle of room
Assembling the Bomb - Kyburz - Lower Workshops secret crawlspace desk
Market Maintenance Code - Pablo Navarro - Lower Workshops crawlspace under stairs
The Vita Chamber - Suchong - Control Room desk left of entrance
Mind Control Test - Suchong - Control Room on table beneath photos
Baby Status - Suchong - Control Room on table beneath photos
Mozart of Genetics - Suchong - Olympus Heights Bistro Square snack bar
Artist Woman - Sullivan - Culpepper's Apartment main room's corner table
Fontaine's Homan Jukebox - Suchong - Suchong's Apartment on floor in south room
Mind Control Antidote - Suchong - Suchong's Apartment on desk next to tonic
Fontaine's Breakup - Paparazzi - Mercury Suites near U-Invent machine on the walkway
Sad Saps - Frank Fontaine - Fontaine's Apartment coffee table near cigars
What's Happening Here? - Diane McClintock - Apollo Square on the ground near Circus of Values
Atlas Lives - Diane McClintock - Apollo Square near Gatherer's Garden
Protection Bond - Suchong - Artemis Suites Suchong's office floor
Meeting Atlas - Diane McClintock - Hestia Chambers right of entrance
The Longest Con - Frank Fontaine - Atlas' Headquarters on desk next of tonic
Today's Raid - Diane McClintock - Atlas' Headquarters in corpse near the safe
Changing Employers - Suchong - Main Hall melt the ice, enter the closet upstairs, search the trash can
Why Just Girls? - Tenenbaum - Atrium Balcony on desk in second floor of orphanage
Extra Munitions - Suchong - Plasmid Prototyping ground near RPG turret
Marketing Gold - Andrew Ryan - Test Subject Storage on machine in right part of room near water
Missing Boots - Suchong - Candidate Conversion Area desk in back of room
Protector Smell - Suchong - Suit Assembly machinery 2nd floor SW
Protecting Little Ones - Suchong - Suit Assembly desk 2nd floor SE room
Mistakes - Andrew Ryan - Suit Assembly near the Gene Bank
Cheap Son of a Bitch - Suchong - Storage small storage area's desk
Slot machine hint:
Save the game before you start playing and keep reloading the game until you hit it.
"Fully Researched Little Sister" trophy hint:
After getting the camera and Hypnotize Big Daddy tonic, find a Big Daddy and follow him until he walks up to one of the wall vents. If you haven't already saved or harvested the Little Sister, he will hit the wall and one will crawl out. Take as many pictures as you can until you can't get any more research, then use Hypnotize Big Daddy. The Little Sister will crawl back into the vent. After Hypnotize wears off, the Big Daddy will hit the wall again, bringing out another Little Sister. Repeat the process to unlock the trophy.
"Little Sister Savior" trophy hint:
Don't harvest a single Little Sister as you play the game. Tenebaum will reward you with gifts (and Adam) every time you rescue three Little Sisters. This is better since you get the same amount of Adam as you would if you harvested them but you also get the trophy hint.
"Tonic Collector" trophy hint:
When buying Plasmids, Tonics, and Upgrades from the Gatherer's Garden, make sure to buy the Tonics first. Then, search every area for other Tonics. When you reach Point Prometheus there will be three Tonics to find, while the rest of the Tonics are available in the Gatherer's Garden. This will ensure you get the trophies. Note: To check how many Tonics you have, go to a Gene Bank and count each "track".
"Brass Balls" and "Seriously Good At This" trophies hint:
Reach the end of the game under the or Normal difficulty and bring Atlas down to his last jar of Adam. Then, pause game play, go to the "Options" menu, and change the difficulty to "Hard". Defeat Atlas to unlock the trophies. Note: You cannot die while unlocking the "Brass Balls" trophy.
Half-Life easter egg:
In the beginning when you first acquire the wrench, Atlas will first suggest the crowbar; the same starting weapon as the main character in Half-Life.
Pac Man easter egg:
In the Arcadia level you will find a place that appears to be a bar. Look around a bit and you will see a block of cheese followed by holes. The cheese is cut like Pac-Man himself and there are holes next to it, none of which can be gun shots. If you shoot the floor with any weapon you have, the marks will not match.
Fight Sander Cohen twice:
Don't kill Cohen after completing his "masterpiece". When you go to the Olympus Heights and get to the area with multiple levels (not Fontaine's house for the poor) to get the second half of the antidote, visit one of the apartments on the first level (to your right from the entrance). This is Cohen's apartment. When he tells you not the disturb the dancers, "knock over" the record player and deal with the upset duo. Cohen himself will then come down to kill you. He can be taken out then. Go upstairs in his apartment (the door to your right upon entering his place) to receive the trophy for entering his apartment and reaching a Power To The People machine. Now, Sander Cohen will not stay dead. Pickpocket his corpse for his Muse key. When you get back on the Bathysphere, go to Fort Frolic and access the Muse (the chained up display) for some decent items, especially if you need first aid kits. Using your chemical thrower (and perhaps anything else), walk to the "masterpiece" and add Napalm and Criticism together, then torch the awful thing. The area will turn red and Cohen will appear for round two. He is a little tougher to kill this time and fights like a Houdini splicer. Pickpocket him again for the same items as last time (including the key for the already opened Muse). He is now permanently dead.
Enemies ignore you hint:
Immediately after receiving The ADOM extractor from the Little Sister, do not take the elevator to the last fight. Instead, go through the rooms you missed along the way. Turrets, Splicers, cameras, and Big Daddies will not see you, and electric trap bolts will not hurt
Ammo Inventor - The player has successfully invented all possible ammo types
Avid Inventor - Successfully invent at least 100 items
Basic Inventor - The player has successfully invented at least one item
Became a Big Daddy - The player has become a Big Daddy
Bought One Slot - The player has purchased one slot in any Plasmid or Tonic track
Broke Fontain's Mind Control - The player has broken Fontaine's mind control
Completed Cohen's Masterpiece - The player has completed Sander Cohen's great masterpiece
Completed Welcome - The player has successfully completed the Welcome To Rapture Level
Dealt with every Little Sister - The player has either Harvested or Rescued every possible Little Sister
Defeated Andrew Ryan - The player has defeated Andrew Ryan
Defeated Atlas - The player has defeated Atlas
Defeated Dr. Steinman - The player has defeated the crazed Dr. Steinman
Defeated Peach Wilkins - The player has defeated Peach Wilkins
Five Fully Upgraded Weapons - Fully upgrade five weapons
Found Cohen's Room - The player has entered Sander Cohen's personal quarters
Four Fully Upgraded Weapons - Fully upgrade four weapons
Fully Researced Thug Splicer - The player has fully researched the Thuggish Splicer
Fully Researched Bouncer - Fully research the Bouncer
Fully Researched Gun Splicer - The player has fully researched the Leadhead Splicer
Fully Researched Houdini Splicer - Fully research the Houdini Splicer
Fully Researched Little Sister - Fully research the Little Sister
Fully Researched Nitro Slicer - Fully research the Nitro Splicer
Fully Researched Rosie - Fully research the Rosie
Fully Researched Spider Splicer - The player has fully researched the Spider Splicer
Hacked a Safe - The player has successfully hacked a safe
Hacked a Security Bot - The player has successfully hacked a security bot
Hacked a Security Camera - The player has successfully hacked a security camera
Hacked a Turret - The player has successfully hacked a turret
Hacked a Vending Machine - The player has successfully hacked a vending machine
Irony - The player has taken a picture of Sander Cohen's corpse
Lucky Winner - Hit the jackpot at a slot machine
Maxed All Tracks - Purchased every slot in all four Plasmid and Tonic tracks
Maxed One Track - The player has purchased every slot in one of the Plasmid or Tonic tracks
One Fully Upgraded Weapon - The player has fully upgraded one weapon
One Successful Hack - The player has performed at least one successful hack
Prolific Photographer - Take at least one photo in every research group
Quality Research Photo - The player has taken a Research Photo of the highest grade
Research PhD - Max out all possible research
Researched a Splicer - The player has taken at least one Research Photo of a Splicer
Restored the Forest - The player has restored the forests of Arcadia
Seriously Good at This - The player has completed the game on the Hard difficulty setting
Skilled Hacker - The player has successfully completed 50 hacks
Three Fully Upgraded Weapons - The player has fully upgraded three weapons
Toaster in the Tub - The player has shocked an enemy in the water
Tonic Collector - Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks
Two Fully Upgraded Weapons - The player has fully upgraded two weapons
Upgraded a Weapon - The player has acquired at least one weapon upgrade
Weapon Specialist - Acquire all upgrades for all weapons
Historian - Find every audio diary
Little Sister Savior - The player has completed the game without harvesting any Little Sisters
I Chose the Impossible - Complete the game on Survivor difficulty without using a Vita-chamber
Brass Balls - Complete the game on Hard difficulty without using a Vita-Chamber
A Man Chooses - Complete the game on Survivor difficulty
I Chose the Impossible - Complete the game on Survivor difficulty without using a Vita-chamber
Platinum Trophy - Earn all Bronze, Silver, and Gold trophies.
"Challenge Rooms" trophies:
"A Shocking Turn of Events"- Collector - Found all collectable Roses in "A Shocking Turn of Events".
"A Shocking Turn of Events"- Expert - Rescued the Little Sister in "A Shocking Turn of Events" in under 4:00.
"A Shocking Turn of Events"- Master Electrician - Charged up the Ferris Wheel 9 different times in "A Shocking Turn of Events".
"A Shocking Turn of Events"- Rescuer - Rescued the Little Sister in "A Shocking Turn of Events".
"The 'I' in Team"- Collector - Found all collectable Roses in "The 'I' in Team".
"The 'I' in Team"- Expert - Rescued the Little Sister in "The 'I' in Team" in under 3:00.
"The 'I' in Team"- Pacifist - Rescued the Little Sister in "The 'I' in Team" without destroying any Machine Gun Turrets.
"The 'I' in Team"- Rescuer - Rescued the Little Sister in "The 'I' in Team".
"Worlds of Hurt"- Collector - Found all collectable Roses in "Worlds of Hurt".
"Worlds of Hurt"- Expert - Rescued the Little Sister in "Worlds of Hurt in under 15:00, on medium or higher difficulty.
"Worlds of Hurt"- Rescuer - Rescued the Little Sister in "Worlds of Hurt".
"Worlds of Hurt"- Tough Guy - Rescued the Little Sister in "Worlds of Hurt" using only plasmids, tonics, the wrench, and the research camera, on medium or higher difficulty.